Oregon vs. USC odds update: Ducks projected to win despite being without star wideout Jeremiah McClellan on Saturday

Sports BettingPublished: Sep. 26, 2026, 4:15 a.m.Oregon tight end Kenyon Sadiq (18) celebrates after his touchdown during the second half of an NCAA college football game against Southern California, Saturday, Nov.

22, 2025, in Eugene, Ore. (AP Photo/Lydia Ely)APLater tonight, the Oregon Ducks (2-1) will travel to Memorial Coliseum for a Big Ten showdown with the USC Trojans (4-0).Last week, the Ducks rebounded after a rough Week 2 loss to Oklahoma State, dominating Portland State 84-0.On the other side, USC enters Saturday undefeated and Jayden Maiava has again been excellent in Lincoln Riley’s offense.However, the Trojans’ defense remains suspect after Rutgers scored 35 points last week, which could open the door for Dante Moore and the Oregon passing attack.At the end of the day, if the Ducks want to jump back into the College Football Playoff conversation, this is a must-win game.Can they get the job done?Below are our updated Oregon-USC predictions, latest odds, and best bet for Saturday night’s ranked Big Ten matchup.Oregon vs.

First reported by OregonLive.